Sullivan, M. R.; Sokkalingam, P.; Nguyen, T.; Donahue, J. P.; Gibb, B. C. Binding of carboxylate and trimethylammonium salts to octa-acid and TEMOA deep-cavity cavitands. Journal of Computer-Aided Molecular Design 2017, 31, 21-28.
Publications
2017
Wang, K.; Gibb, B. C. Mapping the Binding Motifs of Deprotonated Monounsaturated Fatty Acids and Their Corresponding Methyl Esters within Supramolecular Capsules. The Journal of Organic Chemistry 2017, 82, 4279-4288.
Murray, J.; Kim, K.; Ogoshi, T.; Yao, W.; Gibb, B. C. The aqueous supramolecular chemistry of cucurbit[n]urils, pillar[n]arenes and deep-cavity cavitands. Chem. Soc. Rev. 2017, 46, 2479-2496.
This tutorial review summarizes the continuing exploration of three prominent water-soluble hosts: cucurbiturils, pillar[n]arenes and deep-cavity cavitands. As we describe, these hosts are revealing how orchestrating the hydrophobic effect can lead to a broad range of properties and applications, from: nano-reactors, supramolecular polymers, stimuli-responsive biointerfaces, switches, and novel purification devices. We also describe how their study is also revealing more details about the properties of water and aqueous solutions.
2016
Gibb, B. C. Slow Chemistry. Nature Chemistry 2016, 8, 988-989.
Gibb, B. C. Weird and wonderful water. Nature Chemistry 2016, 8, 733-734.
Gibb, B. C. Physics 3 – 0 Chemistry. Nature Chemistry 2016, 8 , 399-400.
Gibb, B. C. The Tip of the Iceberg. Nature Chemistry 2016, 8, 93-95.
Gibb, B. C. From steroids to aqueous supramolecular chemistry: an autobiographical career review. Beilstein Journal of Organic Chemistry 2016, 12, 684-701.
Hillyer, M. B.; Gibb, C.; Sokkalingam, P.; Jordan, J. H.; Ioup, S. E.; Gibb, B. C. Synthesis of Water-Soluble Deep-Cavity Cavitands. Organic Letters 2016, 18, 4048-4051.
Hillyer, M. B.; Gibb, B. C. Molecular Shape and the Hydrophobic Effect. Annual Review of Physical Chemistry 2016, 67, 307-329.
This review focuses on papers published since 2000 on the topic of the properties of solutes in water. More specifically, it evaluates the state of the art of our understanding of the complex relationship between the shape of a hydrophobe and the hydrophobic effect. To highlight this, we present a selection of references covering both empirical and molecular dynamics studies of small (molecular-scale) solutes. These include empirical studies of small molecules, synthetic hosts, crystalline monolayers, and proteins, as well as in silico investigations of entities such as idealized hard and soft spheres, small solutes, hydrophobic plates, artificial concavity, molecular hosts, carbon nanotubes and spheres, and proteins.