A versatile and modular approach to functionalisation of deep-cavity cavitandsvia “click” chemistry

Li, Y.; Giles, M. D.; Liu, S.; Laurent, B. A.; Hoskins, J. N.; Cortez, M. A.; Sreerama, S. G.; Gibb, B. C.; Grayson, S. M. A versatile and modular approach to functionalisation of deep-cavity cavitandsvia “click” chemistry. Chem. Commun. 2011, 47, 9036-9038.

Abstract

The surface modification of deep-cavity cavitands has been demonstrated by using the azide-alkyne “click” coupling to attach dendritic macromolecules or linear polymers onto their periphery. The resulting set of macromolecular cavitands exhibited tuneable solubility yet retained the ability to encapsulate guest molecules.
Last updated on 02/09/2023